It is important to clarify that the following points are not medical advice but only points of reflection to discuss with oncologists, who can best judge whether these approaches and products are appropriate for the individual subject.
In delineating a series of approaches and products, I paste the links to peer-reviewed scientific articles supporting the validity of each approach in oncology. Also, I paste the links to examples of products that are available in the USA. I am not sponsoring any particular brand and the links pasted below are only examples of products that I have used or I have indirect experience with; there exist similar products and I shall be glad to provide my opinion on products from different brands. I also wish to declare my conflict of interest; I have invented some of the products that I mention and, in certain cases, I obtain financial rewards from
their sales. However, I am aware that there are other products with similarcharacteristics that may well suit the scope of secondary prevention. Also, in this case, I shall be glad to provide my opinion on other products. Another important point to be kept in mind is that there is no need to take into consideration or implement all the approaches and products listed below; in other words, although some approaches will synergize with each other, each singular approach or product will effectively work per se. The list is not in order of importance or in any other order.
1. Nutritional ketosis. It is well demonstrated that nutritional ketosis is effective in a number of cancers both as part of treatment as well as for prevention. Nutritional ketosis can be achieved through a dietary regimen that significantly reduces carbohydrates at the same time increasing the uptake of fats, and proteins. Among fats, those with anti-inflammatory properties, such as, for example, extra virgin olive oil, should be preferred. Beta-hydroxybutyrate (BHB), a common supplement, can be added to a ketogenic diet in order to increase the level of ketones. BHB is known to be an effective complementary approach to a variety of
cancers. Achievement of effective ketosis can be monitored by measuring blood ketones (not urine ketones) with common portable devices. According to my experience, levels of blood ketones above 1.5 are effective in oncology. A mild, but still effective, nutritional ketosis can be achieved with intermittent fasting following the Isagenix protocol.

2. Protein metabolism support. We demonstrated that efficient protein metabolism is associated with excellent prognosis even in late-stage, incurable, and untreatable cancer patients, and, therefore, it is all the more efficient in prevention. A good way to support protein metabolism is the approach based on protein shakes, preferably low-carb protein shakes associated with intermittent fasting. This protocol is particularly effective when it is associated with Bravo. Please notice that in our article of 2011, we observed how efficient protein metabolism changed the survival of incurable/untreatable cancer patients from less than 6 months to more than 4 years (see Table 2 of the article). Please also notice that such a difference was observed in the absence of all other approaches and products mentioned in this document since they were not available at that time. Therefore, it can be hypothesized that the addition of the other approaches/products might further improve the preventative properties of protein metabolism support.

3. Microbiome support. In my experience microbiome support is an essential complementary approach that maximizes the efficacy of any type of anti-cancer strategy, whether in the context of treatment or prevention. To this end, in 2011, I invented Bravo an entire ecosystem based on the microbiome that has the goal to empower the immune system so that it can fight cancer in the most natural way. Bravo can be considered a form of natural immunotherapy. Bravo is unique microbiome support that has 100 times higher GcMAF activity than the purified chemical GcMAF that we successfully used in the past (for review on GcMAF, please see this); has powerful detoxifying properties against a number of cancer-associated toxicants; has an array of health-supporting phages that is not present in other products; and has proven effective as a complementary nutritional approach in a number of cancers. A simple explanation of what is Bravo and how it works can be found in the blog of the late Dr. Bradstreet, a world authority in the field of autism. If feasible, I recommend the kit for homemade preparation using the highest quality bovine milk. However, Bravo is also available in the form of capsules or as a non-dairy product based on the fermentation of hemp that has
proven effective in vitro against cancer cells. Bravo oral consumption can be associated with Bravo suppositories.

4. Hyperbaric oxygen. Hyperbaric oxygen is effective in maximizing the therapeutic efficacy of other anti-cancer strategies, both conventional and complementary. Hyperbaric oxygen can also be used in the context of prevention. In vitro, studies demonstrated that it is effective per se. Hyperbaric oxygen is synergic with nutritional ketosis. In the context of prevention, low-pressure
hyperbaric chambers are the most indicated.

5. Regular physical exercise. Also in the case of physical exercise, there is synergy with nutritional ketosis and oxygen. Exercise ideally should consist of aerobic activity at 70-80% of maximal heart frequency, corrected for age, for about 1 hour per day.

6. Anti-inflammatory prevention. A good supplement with powerful anti-inflammatory properties is Triflex. Supplements from other brands containing the same amount of chondroitin sulfate, glucosamine, and methyl-sulfonyl-methane would be equally effective. Reduction of systemic inflammation will cooperate with nutritional ketosis and protein metabolism by reducing the Prognostic
Inflammatory Nutritional Index (PINI score).

7. Mind-dependent strategies. In my opinion, these are more important than all of the above because without an appropriate mindset, the outcomes of either standard of care or complementary approaches will not be those that can be reasonably
achieved and the same can be said for prevention. I recently attended the largest and most representative conference on the subject and I have observed the rock-solid scientific evidence demonstrating the extraordinary power of mind over matter, a power that applies without any doubt to cancer cure as well. There are innumerable techniques even though I have direct experience only with a couple of them; however, I am convinced that there are very many strategies that can achieve the results that I observed. One technique that is accepted by mainstream medicine, and that I have experience with, is visualization or guided imagery. Not to be discounted is also the power of intention including intention by, or from, a healer, the so-called distant healing. For example, the power of intercessory prayer seems to be confirmed both by anecdotal and rigorous controlled meta-analyses that are
posted in the Library of the US Government. Healthy sleep is an essential component of mind-dependent strategies. To this end, I invented Somnium, one of the safest and most potent sleep supports that exist. All information about Somnium can be found here (at the end of the webpage there is a webinar of mine on the subject).

I fully realize that this list is incomplete as well as that each one of the points mentioned above would require pages of explanation. However, with this document my goal is to propose a number of points that I have observed to be very helpful in the management of cancer patients; these same points, adapted to the individual situation can be helpful in preventing recurrences or relapses. Although I am sure that there are other strategies that have proven effective, what I can say is that when I have had the opportunity to observe the implementation of the points mentioned above, the results have been very encouraging.

Respectfully yours,

DR. Marco Ruggiero

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